Think of it as your annual lab work—expanded through a functional medicine lens. The Optimal Health Assessment includes many of the foundational labs commonly checked during routine annual care, while going several steps further with additional biomarkers that provide a more comprehensive look at your health.

Rather than simply screening for disease, this panel is designed to uncover patterns, identify areas that may benefit from attention, and give you a deeper understanding of your metabolic health, nutrient status, inflammation, thyroid function, cardiovascular health, and more.

Your health is unique to you, and having a clear picture of what’s happening inside your body is an important part of feeling optimal. Knowledge is power, and understanding your biomarkers can help identify areas where you may have opportunities to improve, optimize, and prevent future health concerns.

Includes lab orders, a full interpretation from a functional perspective, and a personalized health optimization plan.

Labs can be drawn at a local Quest Diagnostics lab location.

Biomarkers Tested:

• Alanine Aminotransferase (ALT)

• Albumin

• Albumin/Globulin Ratio

• Alkaline Phosphatase (ALP)

• Apolipoprotein B

• Aspartate Aminotransferase (AST)

• BUN/Creatinine Ratio

• Blood Urea Nitrogen

• Calcium

• Carbon Dioxide

• Chloride

• Creatinine

• DHEA Sulfate

• Estimated Glomerular Filtration Rate

• Ferritin

• Folate

• Free T3

• Free T4 Index (T7)

• Globulin (Calculated)

• Glucose (Blood)

• HDL Cholesterol

• Hematocrit

• Hemoglobin (HGB)

• Hemoglobin A1c

• Insulin

• Iron % Saturation

• Iron, Total

• LDL Cholesterol (by calculation)

• LDL/HDL Ratio

• Magnesium (RBC)

• Mean Corpuscular Hemoglobin (MCH)

• Mean Corpuscular Hemoglobin Concentration (MCHC)

• Mean Corpuscular Volume

• Mean Platelet Volume (MPV)

• Non-HDL Cholesterol

• Platelet Count

• Potassium

• Protein, Total

• Red Blood Cell Count (RBC)

• Red Cell Distribution Width (RDW)

• Sodium

• T3, Uptake

• T4 (Thyroxine), Total

• Testosterone, Total

• Thyroid-Stimulating Hormone

• Total Bilirubin

• Total Cholesterol

• Total Cholesterol / HDL Ratio

• Total Iron Binding Capacity (TIBC)

• Triglycerides

• Vitamin B12 (Cobalamin)

• Vitamin D, 25-OH, Total

• White Blood Cell Count (WBC)

• hsCRP

A “normal” TSH should not be the end of the story. The Comprehensive Functional Thyroid Panel checks multiple thyroid markers and antibodies that show the full picture of how your thyroid is functioning.

Biomarker Summary:

• Thyroid-Stimulating Hormone

• Free T4 Index (T7)

• T3, Uptake

• T4 (Thyroxine), Total

• Free T3

• Reverse T3

• Thyroid Peroxidase Antibodies (TPO)

• Thyroglobulin antibodies

Your order includes full interpretation of test results and a personalized health optimization plan based on your results.

Labs are drawn at a local Quest lab location.

The MTHFR gene plays an important role in several processes throughout the body. It helps convert dietary folate into a form the body can use and supports the conversion of homocysteine into methionine—an amino acid needed for protein production and other important cellular processes. Certain genetic variants in the MTHFR gene can reduce the efficiency of this pathway. For some individuals, this may be associated with differences in folate metabolism or higher homocysteine levels, particularly when dietary folate and other B-vitamin status are not optimal. MTHFR Genetic variants can cause:

• Low energy or stamina

• Difficulty with focus or brain fog

• Changes in mood or feelings of stress

• Abnormal laboratory markers, such as elevated homocysteine or low levels of certain B vitamins

• Increased risk of blood clots

• Fertility issues

This test is a simple cheek swab that will be mailed to you. Simply swab and return.

Your order includes full interpretation of test results and a personalized health optimization plan based on your results.

COMT stands for catechol-O-methyltransferase. You can think of this enzyme as your body and brain's cleaning crew. The COMT gene is responsible for giving your body instructions to build an enzyme that clears out stress hormones and brain chemicals. Symptoms of a COMT variant can be:

• lack of focus or motivation

• anxiety

• impulsivity

• chronic fatigue

• heightened stress response

This simple cheek swab is mailed to you and can be self-collected in the comfort of your home.

Included in your order is a full interpretation of your results as well as a personalized health optimization plan.

The DUTCH test assesses your hormone levels in a way no other lab test can. This urine test evaluates how your body produces, uses, and eliminates hormones over time, giving a more dynamic picture of hormone function. This panel includes the Organic Acids Test (OATs), which provides a comprehensive view of possible nutrition, hormone, and metabolite imbalances or deficiencies that can influence overall health, energy, and quality of life. This test requires a urine sample. The kit will be mailed to you.

• Women managing reproductive transitions: Individuals experiencing symptoms of the menopausal transition, irregular or absent menstrual cycles, or severe premenstrual syndrome.

• People with suspected androgen issues: Those dealing with polycystic ovary syndrome (PCOS), acne, unwanted facial hair growth, or hair loss to see how testosterone is metabolized.

• Individuals with chronic stress or fatigue: People suffering from persistent tiredness, sleep disturbances, insomnia, or suspected adrenal dysfunction.

• Those facing weight management struggles: Individuals experiencing unexplained weight gain or weight loss resistance tied to cortisol patterns.

• Men optimizing health: Males looking to evaluate testosterone metabolism, low libido, fatigue, or mood changes.

• Patients on hormone therapy: Individuals using hormone replacement therapy (HRT) or menopausal hormone therapy who need tracking and dosage monitoring.

• Biomarker Summary:

  • 3-Hydroxyisovaleric Acid

  • 4-Hydroxyestrone

  • 2-Hydroxyestrone

  • b-Pregnanediol

  • Indican

  • Total Estrogen

  • Quinolinic Acid

  • Melatonin

  • Estriol

  • Etiocholanolone

  • 8-Hydroxy-2-deoxyguanosine

  • 16-Hydroxyestrone

  • Vanillylmandelic Acid

  • Pyroglutamic Acid

  • Kynurenic Acid

  • Homovanillic Acid

  • 5a-Dihydrotestosterone

  • Xanthurenic Acid

  • Epi-Testosterone

  • 5b-Androstanediol

  • 5a-Androstanediol

  • Androsterone

  • a-Pregnanediol

  • Testosterone

  • Estradiol, Urine

  • Estrone, Urine

  • Progesterone, Urine

  • Dehydroepiandrosterone Sulfate

  • 2-methoxyestrone (2-m-e1)

  • 2-hydroxyestradiol (2-oh-e2)

  • 4-hydroxyestradiol (4-oh-e2)

  • Methylmalonic Acid (MMA), Urine
    

The 3 × 4 Genetic Blueprint is the most personalized approach to your performance, longevity, and wellness. This test is a cheek swab that is shipped to your house. Once you obtain the sample, you simply ship it back and get ready for a health optimization plan built around your genetic composition.

This test analyzes more than 130 genes that represent six main biological pathways in your body:

• Weight and Metabolism: How your body burns carbs, fats, and sugars.

• Inflammation and Recovery: How your body heals and handles swelling.

• Detoxification: How well your system clears out daily toxins.

• Cardiovascular Health: How your heart and blood vessels deliver nutrients.

• Hormone Balance: How your body manages stress and chemical signals.

• Brain and Mood Function: Your mental clarity and stress response

• Genes Tested:

  • APOE

  • COMT

  • MTHFR

  • BHMT

  • CBS

  • VDR

  • NOS3

  • MTRR

  • MTR

  • ADRB2

  • FABP2

  • MC4R

  • OTF

  • TNF

  • SHBG

  • BDNF

  • GC

  • SLC23A1

  • FUT2

  • NBPF3

  • PEMT

  • FADS1

  • FADS2

  • HFE

  • GPX1

  • ADIPOQ

  • PON1

  • HNMT

  • ACE

  • CYP1A2

  • GSTM1

  • CYP2R1

  • APOA5

  • GOD2

  • GSTP1

  • MTHFD1

  • CETP

  • CYP1B1

  • CYP2C19

  • UCP2

  • UCP3

  • ACSL1

  • ADRB3

  • AKT1

  • ALDH2

  • ANK3

  • APOA2

  • APOC3

  • CLOCK

  • COL3A1

  • CYP1A1

  • CYP2C9

  • CYP3A4

  • DRD1

  • DRD2

  • DRD3

  • F2

  • F5

  • FAAH

  • FOXO1

  • FOXO3

  • GABRA2

  • GSTO2

  • HLA

  • ITGB3

  • MMP2

  • MMP3

  • NAT1

  • NAT2

  • NQO1

  • OGG1

  • PPARD

  • SLC2A2

  • SLCO1B1

  • SRD5A1

  • UGT2B15

  • UGT2B17

  • VEGFA

  • ACTN3

  • ACVR1B

  • AGT

  • CACNA1C

  • COL1A1

  • CYP17A1

  • CYP19A1

  • EPHX1

  • GDF5

  • IRS1

  • MMP1

  • OXTR

  • PPARG

  • TCF7L2

  • UCP1

  • ACE2

  • CHRNA5

  • CYP2D6

  • LEPR

  • PPARA

  • SIRT1

  • TAS2R38

  • TIME4

  • AMPD1

  • CKM

  • COL12A1

  • CRP

  • DRD4

  • HIF1A

  • HO-1

  • HTR1A

  • LPL

  • SULT1A1

  • GSTT1

  • IL1

  • PPARGC1A

  • TCN2

  • SOD2

  • OPRM1

  • IL6R

  • DAO

  • IL6

  • PLIN1

  • NFE2L2

  • CAT

Your order includes a full interpretation of test results and a personalized health optimization plan based on your results.

Are you wondering if mold could be contributing to your chronic symptoms? The MycoTOX Profile is a comprehensive mycotoxin test that uses advanced mass spectrometry to screen for eleven different mycotoxins from 40 species of mold in one urine sample.

Biomarker Summary:

• Aflatoxin M1

• Chaetoglobosin A

• Citrinin

• Dihydrocitrinone

• Enniatin B1

• Gliotoxin

• Mycophenolic Acid

• Ochratoxin A

• Roridin E

• Sterigmatocystin

• Verrucarin A

• Zearalenone

Want the complete picture of what is going on inside your gut? This GI-MAP (Microbial Assay Plus) test is truly unique in the field – relying exclusively on quantitative polymerase chain reaction (qPCR) technology to detect parasites, bacteria, fungi, and more by targeting the specific DNA of the organisms tested. The quantitative insights provided in this process, known for accuracy and reliability, allow practitioners to create more personalized treatment protocols for optimizing gut function and addressing dysfunction.

Biomarker Summary:

• Eosinophil Protein X

• Roseburia spp.

• Prevotella spp.

• Klebsiella pneumoniae

• Anti-Gliadin IgA

• Taenia spp.

• Chilomastix mesnili

• Pancreatic Elastase 1

• Faecalibacterium prausnitzii

• Akkermansia muciniphila

• Cryptosporidium spp.

• Giardia

• Lactobacillus spp.

• Fusobacterium spp.

• Bifidobacterium spp.

• Beta-Glucuronidase

• Trichuris trichiura

• Entamoeba coli

• Endolimax nana

• Dientamoeba fragilis

• Candida spp.

• Ascaris lumbricoides

• Helicobacter pylori

• Necator americanus

• Ancylostoma duodenale

• Microsporidium spp.

• Geotrichum spp.

• Epstein-barr virus

• Cyclospora spp.

• Staphylococcus spp.

• Enterococcus spp.

• Escherichia spp.

• Desulfovibrio spp.

• Citrobacter spp.

• Cytomegalovirus

• Enterotoxigenic E. coli

• Bacillus spp.

• H. pylori antibiotic resistance genes

• H. pylori virulence factor vird

• Campylobacter spp.

• Clostridium difficile toxin a

• Clostridium difficile toxin b

• Salmonella spp.

• Shiga-like toxin E. coli stx1

• Shiga-like toxin E. coli stx2

• Steatocrit

• Enterobacter spp.

• Staphylococcus aureus

• E. coli o157

• Yersinia enterocolitica

• Streptococcus spp.

• Proteus mirabilis

• Firmicutes/bacteroidetes ratio

• Firmicutes

• Enteroinvasive E. coli/Shigella

• Blastocystis hominis

• Bacteroidetes

• Vibrio cholerae

• Secretory IgA

• Pentatrichomonas hominis

• Norovirus GI/GII

• Entamoeba histolytica

• Adenovirus 40/41

• Mycobacterium avium subsp. paratuberculosis

• H. pylori virulence factor oipa

• H. pylori virulence factor virb

• Morganella spp.

• Rhodotorula spp.

• Methanobacteriaceae

• Proteus spp.

• Klebsiella spp.

• Citrobacter freundii

• Pseudomonas aeruginosa

• Pseudomonas spp.

• Enterococcus faecium

• Enterococcus faecalis

• Bacteroides fragilis

• H. pylori virulence factor vaca

• H. pylori virulence factor icea

• H. pylori virulence factor dupa

• H. pylori virulence factor caga

• H. pylori virulence factor baba

• Enterohemorrhagic E. coli

• Calprotectin, Stool

• Occult Blood, Stool

• Candida albicans

This test requires a stool sample and will be mailed to you from Diagnostic Solutions Laboratory.

Have you had bloodwork done but still feel confused about what your results mean or what to do next? A functional medicine perspective will help you look beyond individual numbers to understand patterns, explore potential areas for support, and take a more personalized approach to your health.

With a personalized lab review, you’ll receive:

• A clear, easy-to-understand review of your lab results (up to 100 lab markers).

• A functional medicine perspective on your results and potential areas to explore.

• Receive a personalized health optimization plan with recommendations tailored to your individual goals and needs.

Heavy metals testing measures toxic elements such as lead, mercury, cadmium, and arsenic that can affect energy, mood, and long-term health. With US BioTek’s precise urine analysis, practitioners can detect hidden exposure, evaluate toxic load, and create effective detoxification plans. The urine collection kit and instructions will be mailed to you and you will ship your sample back to the lab.

Biomarker summary

• Iodine, Random Urine

• Arsenic/Creatinine Ratio, Urine

• Mercury/Creatinine Ratio, Urine

• Lead/Creatinine Ratio, Urine

• Magnesium, Random Urine

• Aluminum/Creatinine Ratio, Urine

• Antimony/Creatinine Ratio, Urine

• Barium/Creatinine Ratio, Urine

• Bismuth/Creatinine Ratio, Urine

• Cadmium/Creatinine Ratio, Urine

• Gadolinium/Creatinine Ratio, Urine

• Nickel/Creatinine Ratio, Urine

• Thallium/Creatinine Ratio, Urine

• Tin/Creatinine Ratio, Urine

• Titanium/Creatinine Ratio, Urine

• Tungsten/Creatinine Ratio, Urine

• Uranium/Creatinine Ratio, Urine

• Cesium/Creatinine Ratio, Urine

• Germanium/Creatinine Ratio, Urine

• Platinum/Creatinine Ratio, Urine

• Rubidium/Creatinine Ratio, Urine

• Copper/Creatinine Ratio, Urine

• Lithium/Creatinine Ratio, Urine

• Selenium/Creatinine Ratio, Urine

• Zinc/Creatinine Ratio, Urine

• Beryllium/Creatinine Ratio, Urine

• Boron/Creatinine Ratio, Urine

• Bromine/Creatinine Ratio, Urine

• Calcium/Creatinine Ratio, Urine

• Chromium/Creatinine Ratio, Urine

• Cobalt/Creatinine Ratio, Urine

• Gallium/Creatinine Ratio, Urine

• Iron/Creatinine Ratio, Urine

• Manganese/Creatinine Ratio, Urine

• Molybdenum/Creatinine Ratio, Urine

• Palladium/Creatinine Ratio, Urine

• Silver/Creatinine Ratio, Urine

• Strontium/Creatinine Ratio, Urine

• Tellurium/Creatinine Ratio, Urine

• Vanadium/Creatinine Ratio, Urine

• Zirconium/Creatinine Ratio, Urine

Give someone you love the opportunity to invest in their health and better understand their body. A Functionally Well gift card can be used toward any Functionally Well lab offerings, providing access to personalized functional and integrative healthcare designed to look deeper, uncover contributing factors, and support optimal wellness. There are few gifts more valuable than feeling your best.